After several of Bailey's patients die, she becomes the focus of a CDC investigation; Cristina teases Alex about his feelings for Jo; Owen continues to take care of Ethan while his parents remain in the hospital.
The investigation into the death of a woman's husband reveals that the deceased man was living a double life.
The squad works overtime hunting down a serial killer; Maura befriends a witness to the crime who suffers from a medical condition that causes him to believe he is a wolf.
Castle is captured and forced to work with strangers to solve deranged puzzles and mind games, while Beckett and the 12th precinct must race against time to rescue Castle and catch a killer.
A notable county prosecutor is arrested for murder. Angela hears that Maura is planning to meet Jack's daughter, and she sets out to educate Maura about the interests of children today.
