Based on the best-selling self-help book that's a social commentary about modern day relationships and the age-old problems of misunderstanding the opposite sex, He's Just Not That Into You stars Drew Barrymore and a veritable who's who of romantic comedy stars and starlets including Oscar winners Jennifer Connelly and Ben Affleck, Entourage's Kevin Connolly, The Hangover's Bradley Cooper, "Mac Guy" Justin Long, Big Love's Ginnifer Goodwin, Friends' Jennifer Aniston, Vicky Cristina Barcelona's Scarlett Johansson and many more. A virtual Traffic of romantic comedy, the film's interconnecting story arcs connect each character with the others in an off-the-wall comedy of errors where the social faux pas rule the day.