Oprah Winfrey

Deborah Lacks

Rose Byrne

Rebecca Skloot

Renée Elise Goldsberry

Henrietta Lacks

Rocky Carroll

Sonny Lacks

Courtney B. Vance

Sir Lord Keenan Kester Cofield

Reg E. Cathey

Zakariyya

Reed Birney

Dr. George Gey

Leslie Uggams

Sadie

John Benjamin Hickey

Bill Watson

Ruben Santiago-Hudson

Dr. Pattillo

Byron Jennings

Dr. Victor McKusick

John Douglas Thompson

Lawrence

Roger Robinson

Day Lacks

Adriane Lenox

Barbara

Gabriel Ebert

Dr. Christoph Lengauer

Peter Gerety

Paul Lurz

John Beasley

Cliff

Kyanna Simone Simpson

Young Deborah Lacks

George C. Wolfe

Director

Alan Ball

Producer

Peter Macdissi

Producer

Oprah Winfrey

Producer

Carla Gardini

Producer

Lydia Dean Pilcher

Producer

Peter Landesman

Writer

Alexander Woo

Writer

George C. Wolfe

Writer