McGarrett and Danny go undercover as drug pilots to stop a meth epidemic on the island. But when McGarrett is seriously wounded, Danny is forced to break cover and land the plane.
Coulson and the team attempt to redirect the course of humanity's fate, but they're unaware what impact their efforts will have on one agent's life.
Rosie and Villa must establish the true identity of a murder victim who appears to have died three years prior; TMI attempts to reconnect with Pippy; Donna struggles to keep a secret from her family.