The doctors compete for Richard's affections; a surgical patient endangers the lives of those around her; Meredith's mother, who has Alzheimer's disease, experiences a change in her medical condition.
Morgan begins to question his faith when the BAU hunt for a cannibalistic serial killer terrorising citizens of Seattle. Garcia's first date with the man of her dreams comes to an unexpected end.
The day of Brick's birth has been kept a family secret for nine years; Axl finds his new manager attractive but incompetent.
Charlie shows up in New York, sidelining Betty's plan to spend her birthday with Henry; Wilhelmina tries to ruin Renee's blossoming relationship with Daniel by hinting that there are dark secrets in her sister's past.
When three homeless men seek Monk's services at the holidays, Natalie convinces him to investigate their friend's death; Stottlemeyer's faith reawakens when a visit to a monastery fountain rids him of crippling pain.