The doctors of Grey Sloan Memorial must contend with the COVID-19 pandemic; an unintentionally started fire has first responders from Station 19 bringing patients into the hospital for treatment.
Bailey finds herself in the middle of an argument with patients' families as they await news about their children who were injured in a fire; Winston surprises Maggie; Amelia and Link try to have some fun as new parents.
The Reagans come up against an international drug lord when a decorated detective is kidnapped. Meanwhile, Len accompanies Jamie on a ride-along.
McGarrett and Grover are given orders to serve a warrant to a young computer hacker as a matter of national security.
After a 16-year-old kidnap victim escapes her captors, her parents hire Magnum, who experienced similar trauma as a POW, to find who took her.