Gil Grissom and Sara Sidle come to the aid of a former colleague who is implicated in tampering with evidence; Maxine and the rest of the CSI team work the murder of a couple slain on their wedding day.
Catherine Willows persuades Maxine Roby to let her rejoin the team; a dominatrix is found murdered near her secret sex dungeon.
When David Hodges goes missing, the team search for any piece of evidence to help locate him, clear his name and save the reputation of the crime lab.
Max puts CSI on lockdown when evidence in a new murder tips Grissom and Sara to a new suspect in the crime lab; Folsom and Allie investigate a series of chilling killings at a dilapidated clown-themed hotel.
When three masked assailants invade a home and murder an entire family, the team is called to the scene to investigate. Catherine leads the team through the emotional case, which intensifies her own longing to reconnect with her estranged daughter.