An old friend of Sebastian's asks for help when her business partner is murdered at a gaming convention. Meanwhile, FBI Special Agent Raymond Isler believes Adrian to be the hacker that Cyber Crimes has been tracking for years.
Bull puts aside his personal grievances with AUSA Reilly, who prosecuted him for jury tampering, to help bring one of the world's most dangerous drug lords to justice. The pair enter into a hesitant partnership.
Mac and Jack face a family of bounty hunters on a mission to find a fearsome fugitive while hackers target a personal file.
Michael questions his motives when he is assigned to take down a drug smuggler; Fiona and Jesse want to learn more about the organisation's leader.
Both sides of McCall's life converge when her daughter Delilah and her school friends are threatened by a European crime syndicate for being eyewitnesses to the outfit's execution of a drug cartel boss.