Cristina treats a former Seattle Grace scrub nurse and is forever changed. Izzie's past comes back to haunt her and makes a case difficult.
Miami cops are tasked with finding the killer of the assistant DA's younger brother. Meanwhile, Dexter and Rita move closer to making a decision about their family.
Prado begins to wonder if Dexter is to blame for a second murder victim, who turns up after Freebo is out of the picture.
A husband who had killed two of his wives for financial gain is Dexter's new candidate, but his relationship with Rita complicates the situation.
After deciding to be an involved father, Dexter proposes to Rita, prompted by Astor's questioning of their relationship.