At the forefront of the Sexual Revolution, Masters and Johnson are about to publish their study, finally removing the shroud from the work that’s consumed them for the past decade. As they face the press for the first time, they flashback to a summer vacation of the year prior, where Virginia is faced with parenting struggles, Bill is finishing work on their book, and Libby is pulling herself out from beneath a deep depression.
The shockwaves surrounding the events of Masters and Johnson’s first press conference begin to reverberate around their universe as the book nears its release date. Bill takes on a powerful, high profile fertility patient with the help of a new doctor in the practice, while Virginia and Libby come to terms with Bill’s role in Gini’s life.
As Masters (Michael Sheen) looks to have their book accepted into the medical school curriculum, Johnson (Lizzy Caplan) courts potential investors to popularize their work.
As Masters (Michael Sheen) looks for ways to improve sales of their book, Johnson (Lizzy Caplan) focuses on her son’s health problems in Vietnam. Margaret Scully (Allison Janney) and her new boyfriend seek help at the institute.
A visit by her parents threatens to expose Johnson’s (Lizzy Caplan) secret. As Margaret’s (Allison Janney) unconventional living arrangement is revealed, Masters (Michael Sheen) returns to face his former colleagues.
As Johnson (Lizzy Caplan) pushes back against her mother’s matchmaking scheme, Masters’ (Michael Sheen) plan to spend time with his son backfires. Libby (Caitlin Fitzgerald) reveals the truth about her comatose neighbor’s plan to leave her husband.
Michael Sheen
William Masters
Lizzy Caplan
Virginia Johnson
Caitlin FitzGerald
Libby Masters
Nicholas D'Agosto
Ethan Haas
Teddy Sears
Austin Langham