Chase and his two best friends, Bren and Jinja, learn that Jeredy is missing. Jon Ace and S.T.O.R.M. join Chase at the lab but it is soon revealed that they are after the fully-loaded Core that Jeredy left behind for his son.
When scientist Jeredy Suno activates an alien DNA he inadvertently unleashes a power that could destroy the world. However, Jeredy also created the powerful Monsuno monsters. Now it is up to his son, Chase, to learn the secrets of Monsuno and help save the world from impending destruction.
The trio heads to Axistown where they meet a mysterious woman who sends them to an underground fight club; Jinja obtains her own Monsuno she calls Charger.
Chase heads to an abandoned facility in search of his father only to end up fighting Darkspin and Medea.
After being captured by the evil Bookman, Chase, Bren, and Jinja must team up with a monk named Beyal in order to escape.
STORM sets up a blockade to keep anyone from leaving Mandala so Chase becomes convinced that he and his friends must attack STORM.
Christopher Corey Smith
Bren/Jon Ace/Bookman/Mr. Black
Keith Silverstein
Dax/Commander Trey/Master Ey/Lat
Karen Strassman
Jinja/Commandant Marshal Charlemagne/Medea/Grandma Future
Kirk Thornton
Beyal/Hargrave/Tel/Arg