When Ms. Frizzle's younger sister takes over as the class's teacher, the students are surprised. Arnold is concerned about what it could mean for their classroom, but his friends are open to the change.
The class needs to strengthen the set for their theatre performance after receiving some constructive criticism, and find inspiration on a trip to the world's windiest mountain.
On a trip to Hawaii, the class learns more than they expected about the tiny fish and the sharks in the ocean when Wanda dedicates herself to helping one of the fish.
When Tim lacks inspiration for his time capsule comic book, the class takes a trip to Iceland to find out who would win between their comic book superheroes Weatherman and Captain Rock Man.
Ms. Frizzle takes the class on a trip of microscopic proportions to learn from experts and save Ralphie's floundering dancers from ruining his variety show.
Carlos wants to convince the principal to let him keep a rat in the classroom but has to do something about his cold first, so the class take a trip to get to the source of the problem.
Kate McKinnon
Ms. Fiona Frizzle
Miles Koseleci-Vieira
Arnold
Lynsey Pham
Wanda
Mikaela Blake
Keesha
Gabby Clarke
Dorothy Ann