When Padma's pregnancy takes a dangerous turn, the doctors come together to find a solution and turn to Ian to perform a miracle; Conrad makes a decision regarding his love life and Devon leads his own clinical trials at Chastain.
Conrad takes Trevor under his wing to care for a patient whose good luck seems to have run out; Leela struggles when given the decision to take full responsibility of her indecisive patient's life.
A new group of interns, which include Billie's son, start their first day; Kit and Bell try to convince Conrad to come back to Chastain; Leela and Padma deal with an unexpected visit from their parents.
Conrad and Cade work with a Medicare patient who sheds some light on the inner workings of the prescription fraud situation; Leela works herself to the brink of exhaustion to avoid having a conversation with Devon.
When things from Billie's past begin to come to light, the team struggles to find the best way to support her; with the nurse shortage in full swing, a simple cleaning job turns into a horrific disaster.