Melinda tracks down a girl who has been missing for 12 years and discovers a long-held secret.
Masters and Johnson prepare to publish their study; Virginia faces parenting struggles; Libby pulls herself out of a depression.
The book nears its release date; Masters takes on a high-profile patient; Virginia and Libby come to terms with their roles in Bill's life.
Masters and Johnson seek new partners to help put the past behind them; Libby reevaluates her relationship with Bill and Virginia.
Virginia's parents arrive unannounced; Masters takes on a promising fertility patient.