Cameron makes a startling discovery.
A bad day causes Penny to reevaluate her life choices - including Leonard. Howard and Bernadette struggle to care for Mrs. Wolowitz.
Ron gets married, Leslie goes to London to receive an award, Ben and Andy try to get a grant from a rich Englishman, and Tom discovers the identity of his new business rival.
Ron's honeymoon doesn't go as planned, Leslie gives an unpopular speech at her award ceremony, Andy considers a business proposal, and Tom attempts to compromise with his rival.
Alberta's expertise from her past comes in handy when Sam and Jay run into some complications during their Woodstone whiskey tasting soiree; Trevor devises a ghost fraternity, which inspires a revelation from Isaac's past.
