Cameron makes a startling discovery.
A bad day causes Penny to reevaluate her life choices - including Leonard. Howard and Bernadette struggle to care for Mrs. Wolowitz.
Ron gets married, Leslie goes to London to receive an award, Ben and Andy try to get a grant from a rich Englishman, and Tom discovers the identity of his new business rival.
Ron's honeymoon doesn't go as planned, Leslie gives an unpopular speech at her award ceremony, Andy considers a business proposal, and Tom attempts to compromise with his rival.
Max is embarrassed when she discovers Sebastian (guest star Jesse Metcalfe — Dallas, Desperate Housewives), the hot guy she's been spending time with, is a DJ — at a grocery store.