Seven-year-old Jack is undergoing his 22nd operation; Jack has a range of genetic conditions, which have led to him having both of his kidneys removed.

Follow the work of staff and progress of kids at the Royal Manchester Children's Hospital, now the largest hospital for children in the UK.

Fourteen-year-old DJ Lockley from Salford is a medical miracle who wasn't expected to survive birth.

Follow the work of staff and progress of kids at the Royal Manchester Children's Hospital, now the largest hospital for children in the UK.

Six-year-old Emily Fish has a rare blood disorder and needs a bone marrow transplant, but it will require weeks of grueling chemotherapy; in A&E, a 14-year-old boy has convinced himself he needs a leg amputation, and a baby has a full-body rash.

Jack meets surgeon Andrew Henry to find out if an operation to repair his hip has been a success.