The doctors of Grey Sloan Memorial must contend with the COVID-19 pandemic.

An unintentionally started fire has first responders from Station 19 bringing patients into the hospital for treatment; Amelia and Link try to have some fun as new parents.

An elusive girl may hold the key to a mystery that brings the team to Asia; a secret jeopardizes Skye's relationship with the team.

Sookie hatches a dangerous plan to take down the H-Vamps, even as Vince and his armed vigilantes pose an equally serious threat. Lafayette gets high with James; Jason eyes a family future with Violet; Willa is forced to find a new place to stay; Sarah Newlin sheds her past. Pam offers Eric a compelling reason to return to Louisiana--and be the vampire he used to be.

Holmes and Watson get involved with nuclear security when they investigate the murder of a former Japanese crime syndicate gang member; Capt. Gregson is blindsided by a stunning personal confession from his daughter, a police sergeant.