Mike's incompetence threatens to ruin Frankie's Mother's Day; Mike tells Axl, Sue and Brick to put some effort into a gift for Frankie; Frankie asks the kids how they would differ from her as parents.
A chance encounter with a military colonel (guest star Aaron Raymond) leads Jane to believe the officer is hiding something, prompting him to dig into the closed murder case of the man's wife.
Out of consideration for Derek, Meredith stops talking about her surgeries; Richard asks Dr. Avery to help with a complicated procedure; Callie and Alex face their guilt.
House and team wrestle with an ethical dilemma when a patient asks them to help him end his life.
Leslie and Ben start new jobs; Donna, April and Andy prank Ben; Tom readies himself for a big presentation; Ann and Chris consider the future.