Topher's mother lands in the ER with mysterious symptoms; Drew and Shannon treat a badly injured foster mom and make a discovery.
During a series of rolling blackouts, the team tracks a serial killer in Los Angeles who targets families.
While Maura is away at a convention, Jane needs Susie's help to solve a murder; Korsak is forced to deal with painful unfinished business.
When it appears one of their own shot an unarmed man on a Boston subway platform, the team must find the real killer while clearing their detective's name.
A killer uses online ads to find perfect candidates for murder: men no one notices are missing. Meanwhile, Jane finds that keeping her pregnancy quiet will be a tough assignment.