Desperate to prove that he is good, Jack enlists a dreamcatcher named Kaia to help him save Mary Winchester from the alternate universe.
When Sam and Dean go missing, Jody Mills calls on Claire Novak to help find the Winchesters; some women coalesce and head off on the most important hunt of their lives.
Joel scurries to complete Jesus' mission; Gus and Cobi each deal with the authorities holding them accountable for their crimes; while in surgery, Lex has an ethereal encounter.