Former CIA operative Dr. Dylan Reinhart (Alan Cumming) is lured back to his old life when NYPD detective Lizzie Needham (Bojana Novakovic) needs his help to stop a serial killer, on the series premiere.
Dylan, having returned to teaching after helping the NYPD catch a serial killer, is called upon again to aid Detective Needham on a complex case involving the murder of a venture capitalist.
The murder of a young man who recently left his family's religious community leads Dylan and Lizzie to a series of possible suspects; Lizzie's younger sister unexpectedly drops by for a visit.
Dylan and Lizzie are assigned to a murder in Central Park after their investigation into a chemical attack on the subway is taken over by the FBI.
Dylan and Lizzie investigate the murder of a Jane Doe but learn that the victim was killed by mistake; they must identify the killer's intended target before she suffers the same fate.
Dylan and Julian go under cover in a hospital to catch an "angel of death" who is killing patients who have non-life-threatening ailments; Lizzie asks Andy for his legal expertise when a personal trainer sues her for accidentally injuring him.
Dr. Dylan Reinhart
Det. Lizzie Needham
Lt. Jasmine Gooden
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