Everyone's lives on Wisteria Lane are forever changed when Carolyn Bigsby holds shoppers hostage at a local supermarket. Meanwhile, Gabrielle and Carlos finish dividing their assets: Gabrielle gets the house, and Carlos gets everything in it.
A prophetic ghost shares visions of a deadly future with Melinda, making her fear for her loved ones.
The remains of a teenage runaway are discovered and his parents think he was murdered by his "wrong side of the tracks" girlfriend. When it becomes apparent that she is interested in tragic love stories, i.e., addicted to Romeo and Juliet, Bones and Booth are about to concur, but new evidence leads them to believe a man helping runaways may be involved.
McGill orders Curtis to take Jack into custody for violating presidential orders, but Jack breaks away from Curtis when Nathanson contacts him and offers information on the location of the nerve gas. McGill begins to unleash on his coworkers as he discovers that they may be working against him to aid Jack.
Agent Bauer deals with the federal agent, a defector, who recruited him to counterterrorist work more than a decade earlier.