While at the hospital, Claire and Phil see an older version of their family; Manny and Jay visit a private school; Mitch and Cam organize a day for Gloria and Lily.
It's father-daughter time, as Phil takes Haley on a college tour of his old alma mater, and Claire, having a rare night alone, forces Mitchell and Cameron to take her for a fun night out with the boys -- but ends up alone with one particular man candy who is anything but gay. Meanwhile, Gloria and Jay deal with a potential situation at home that may require having "the talk" with Manny. Guest starring Gilles Marini.
In the 12th season premiere, Sam and Kovac report to the police that her diabetic son, Alex (recurring guest star DOMINIC JANES), is missing and is possibly trying to find his father. The boy mistakenly thinks his dad is in Colorado, but the man is actually incarcerated. Unfortunately, Alex left without his insulin. And Neela, Ray and Abby struggle with their first shifts in charge of the new interns.
Betty's life is turned into turmoil after the numerous upsetting events that have recently occurred. Despite all this, she refuses to accept the fact that Henry's leaving has deeply affected her. Meanwhile, Amanda has a hard time coping with the news she recently discovered about who her real mother is and Wilhelmina plans to use all the recent tragedies to her advantage.
Ruth sets ground rules for a new live-in apprentice; David meets an old acquaintance; Claire is surprised by her responsibilities as Oliver's new assistant.
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