Dhama Chaukdi is a story of four underworld dons Mani Aiyer from Madras (Mukesh Tiwari), Pappu Yadav from Bihar (Akshay Yadav), Lallan Pyare from UP (Deepak Chauhan) and Sanjay Apte from Aamchi Mumbai (Yadhuveer Yadav) who are staunch enemies with their businesses in Mumbai. They would willingly give one eye if it means blinding the two eyes of the other.