Michael and Lincoln face the fact that everything they worked for may have been for nothing. Bellick finds himself back at Fox River, and T-Bag continues to leave a trail of bodies in his wake as he hunts down the woman who turned him in.
Bull finds himself serving jury duty while simultaneously mounting a defense for a woman on trial for killing her daughter's murderer.
Michael finds himself trapped inside a private bank with Jason Bly during an armed robbery. Meanwhile, Michael's predicament disrupts Sam's love life.
Buddy Garrity is forced to tell Lyla about his financial troubles; when J.D. meets a girl at school, his father worries he is losing his focus on football.
When a teenage girl is found dead, the investigation leads Walt and the team to the illegal sale of prescription drugs. Meanwhile, Henry reconnects with an old flame and Cady returns home.