A blackout requires staff to treat patients without technology, so Bell orders the staff to stop accepting new patients. Conrad and Devon go against the mandate to help a child, and Mina and Austin must perform heart surgery.
Bell decides to use a new medical device company rather than the hospital's usual products. Kit and AJ must stop their feuding to team up against him. Conrad and Nic work to make a child's dreams come true.
The doctors of Chastain are surrounded by new rules and doctors, as Red Rock Mountain Medical takes over the hospital.
After a long wait, Conrad and Nic prepare for their wedding day; flashbacks to the early days of the COVID-19 crisis shine a light on the heroism of the doctors and the toll the virus took on everyone at Chastain Memorial.
Devon and Irving are inundated with patients in the ER on Thanksgiving, while an A-list celebrity also seeks treatment at the hospital.