Halstead puts his career on the line to solve a case involving his new girlfriend. Meanwhile, Voight discovers Ruzek is a mole but works with him to take down Woods.
Dr Manning and Dr Marcel disagree over an abusive husband. Dr Halstead struggles with ethics and his decision to work at the safe injection site. Dr Charles and Elsa reveal a misdiagnosis that may change a family's life.
LeBlanc and Shea discover Ted's plan for the NEXT server and race to intervene before it is too late; Ben and Gina investigate NEXT's latest victims after a freak accident occurs; Shea reaches her breaking point.