While Meredith faces the repercussions of messing with the medical trial, April tries to step up at Chief Resident; Cristina and Owen disagree.
The eldest daughter of a family involved in a car crash must make a difficult decision; Teddy asks Cristina to help with an O.R. patient; Lexie works with Mark's new girlfriend during a surgery.
Work and personal pressures leave Meredith on edge; formal interviews for the chief resident position begin; Lucy and Alex's relationship is tested.
Meredith's dishonesty is revealed, leading to unexpected consequences for her and others; the new chief resident is chosen.
The residents try to impress Jackson's mother, Catherine Avery, when she comes to Seattle Grace to perform a groundbreaking surgery.