While Meredith faces the repercussions of messing with the medical trial, April tries to step up at Chief Resident; Cristina and Owen disagree.
Meredith and Derek's relationship concerns Zola's adoption counselor; Alex notices he has become an outcast; Cristina makes a difficult decision.
The squad tries to solve a homicide case that is muddied by conflicting evidence, Maura must decide if she is going to take in her recently paroled grandfather, and Jane and Casey must decide between their careers and their relationship.
When a six-year-old boy is brought in with the same symptoms as another patient who died years ago under House's care, House believes the cases are identical and he can predict the course of the boy's illness. Meanwhile, the clinic hosts a poker night to benefit the oncology department.
After a notorious serial killer is executed, a copycat begins murdering women in the same Oklahoma town and in the same fashion, and the BAU team must act fast before more victims are found.
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