Despite everyone else's doubts, Shaun is hopeful that Carly is truly fine with his friendship with Lea. The team treats a young boy born without a fully formed trachea who may be a good candidate for an experimental procedure.
When a nuclear-powered Russian satellite is knocked out of orbit, the new Director of Homeland Security Adriana Molina reunites the Scorpion team and puts them into action. Elsewhere, Paige and Walter confront their feelings.
Amid several life-altering moments on the home front, Bravo Team travels overseas to extract a CIA agent who is being held hostage.
Jimmy's brother Billy and his family invite themselves over to celebrate Thanksgiving with the DiMeos.