Dog's Best Friend: Cutest Canine Companions

There are over 100 animals at the T.I.G.E.R.S. preserve in Myrtle Beach, S.C., a place that offers visitors first-hand interaction with wild animals; hound dog Roscoe's best friend is an orangutan named Suria.

At Columbus Zoo and Aquarium in Powell, Ohio, a Labrador retriever called Carlisle is friends with a pack of cheetahs, the fastest land animal on Earth and an equally social species.

A friendship reaches new heights when a hunting dog makes friends with a creature who could have been his prey; husky puppy Bailey makes an unlikely friendship with a Ragdoll cat called Leon.

Born with a birth defect, rescue dog Roo's front legs never fully develop; a local Beirut rescue saves Roo and sends her to Canada in the hope of a better life, where she strikes a strong bond with another rescue dog.

At an ecotourism zoo in Florida, a dog that is a bundle of relentless energy is put in with another spirited playmate, a tiger cub who was rejected by his mother at birth.

The Lenihans are almost like a modern-day circus family, tending a sum of 30 animals; their family dog Hondo, a German shepherd mixed breed, has no shortage of playmates but chooses a solitary coati-mundi to be his best friend.