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Frankie Maddox is a witty, good-natured nurse who manages her team well but has a take-no-prisoners approach. She often goes above and beyond the call of duty to care for her patients and is sometimes accused of getting too attached and too involved with her patients. But she always does what she can to ensure the best for them. When she's not at work, Frankie enjoys spending time with her long-term boyfriend, Ian, who works as a uniformed PC. Frankie's confidante and co-worker is former Army medic Andy.