The series `Open House: The Great Sex Experiment' explores whether relationships can thrive without monogamy. In a bold social experiment, a group of monogamous couples are asks to challenge their views and consider for the first time if they would be happier in open relationships. Relationship coaches and sex therapists assist the couples in their journey, as they challenge the notion that having sex with other people is at odds with being in a committed relationship. However, it is not all plain sailing, as the couples discover the difficulties involved with abandoning monogamy.