A huge shipment of contraband cheese disappears leading the Federal Mousehole of Investigation to send its three best agents - Elliot Mouse, Gordon and Mr Wilson - to Cheesecago.

Following their eventful arrival in Cheesecago, Elliot Moose, Gordon and Mr Wilson spend the night in Jack's garage, safe from Al Catone's thugs.

Elliot Mouse and the Untouchables try to bring Al Catone's empire down by dealing a hard blow to his main source of income: contraband cheese.

Al Catone continues his bootlegging by pirating the cheese shipped across Lake Michicat by local businesses and then introducing it in Cheescago by way of a secret route.

The Untouchables' fight against Catone encourages the collaboration of the city's residents who leave secret messages for the Feds at the Cheese Paré. Due to the danger incurred, the club is visited by a dwindling number of customers.

Sandra La Flame, a stunning cabaret artist, debuts at the Montmarte Club, owned by Al Catone, where her boyfriend Thomas works as a waiter.