Dr. Manning and Dr. Marcel disagree over an abusive husband; Dr. Halstead struggles with ethics and his decision to work at the safe injection site; Dr. Charles and Elsa reveal a misdiagnosis that may change a family's life.
LeBlanc and Shea discover Ted's plan for the NEXT server and race to intervene before it is too late; Ben and Gina investigate NEXT's latest victims after a freak accident occurs; Shea reaches her breaking point.