The crash survivors must make a life-changing decision; tensions escalate between Jackson and April; Alex tries to restrain himself.
When a lost child is brought in with physical signs of abuse, Conrad and Cade try to get to the bottom of what happened to her; while out shopping, Devon and Leela encounter a woman who is having trouble breathing; Billie confronts her past.
When one of Chastain's own is brought into the emergency room with life-threatening injuries, the staff tries to save her life, while disagreements over how to best handle her care put Cain at odds with the rest of the doctors.
With Chastain on the verge of shutting down due to the sale by Red Rock, Conrad tries a last-ditch effort to save the hospital; the doctors plan for their next career moves; Nic is injured by a deranged patient.
Conrad finds himself caught between his duties as a doctor and his loyalty to Kit, when he discovers that her son-in-law may be suffering from a serious disease. Devon and Nic make a shocking discovery about a former patient.