Troy Landry, his son Chase and snake expert Bill Booth track serpents into a breeding ground known as Deer Haven; veteran swamper Bruce Mitchell and invasive species hunter Zak Catchem take on the legendary Skunk Ape Alley.
As the hunting season heats up, Troy, Chase and Bill dive into deep water to catch pythons, but could be in over their heads.
The hunters venture into the Everglades Triangle, an area known for mysterious disappearances and swarms of snakes; Troy, Chase and Bill use a drone to search the swamp from the air, while Bruce and Zak track snakes with a handheld thermal device.
A mishap could leave Troy, Chase and Bill stranded overnight, while Bruce and Zak's journey to an abandoned town leads them to an unexpected opportunity.
Troy, Chase, and Bill gamble on a long journey into the centre of the Everglades, following the migration of giant pythons to the furthest depths of the wetlands.
A friendly wager on which team can catch the most snakes and the biggest python; Troy, Bill and Chase return to a honey hole from last season, while Zak and Bruce place their bets on an abandoned Cold War bomb shelter.
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