US President Ronald Reagan has been shot. Elizabeth and Phillip are up against the clock and the FBI in trying to find out who is responsible and whether they need protecting.
Max goes head-to-head with hospital administration when he comes up with a new plan for patients without insurance. Iggy struggles with an accusation brought against him. Sharpe navigates her role as deputy medical director.
Max is forced to reckon with his diagnosis in a new way as things become more difficult for him. Meanwhile, Reynolds is forced to address what could have gone wrong in a recent surgery.
As Elizabeth tries to thwart a power grab after an earthquake kills the Venezuelan president, her brother is moved to help the relief effort.
While Elizabeth looks for a diplomatic way to handle a cult in Bolivia, the group takes a congressman hostage; Stevie introduces her boyfriend to Elizabeth and Henry.