Patrick Jane wordt persoonlijk betrokken bij de zaak van een vergiftigde professor als de hoofdverdachte de vrouw van het slachtoffer en tevens zijn voormalig psychiater is.
Chandler finds himself making a difficult decision when an order comes in from the White House.
Tom Chandler goes to Asia to investigate a possible mutation of the Red Flu; Captain Slattery and his crew deliver the cure to Southeast Asia.
Chandler gets a lead that may help answer some dangerous questions; Kara does an investigation in the White House.
As Chandler's position worsens, his mission becomes increasingly complicated; President Michener faces pressure from the regional leaders.