Grace's freeloading sister (Geena Davis) comes to town to launch her latest business enterprise; Karen spurns Lyle (John Cleese), then changes her mind after Lorraine (Minnie Driver) expresses her disapproval.
Will and Grace try to break up Jack and Stuart (Dave Foley) so they can sell the apartment for a higher price; Karen demands that Lyle (John Cleese) discipline his daughter (Minnie Driver).
Will and Grace begin a business venture selling apartments; Jack runs into his former acting mentor, Zandra; Karen and Lyle (John Cleese) try to renew romance.
Will takes his mother for an afternoon stroll and bumps into an attractive bachelor (Dylan McDermott); Karen continues her lifelong quest to hunt down hubby-stealing Lorraine.
Terwijl mevrouw Ari woedend is over Ari's woedeaanval de avond ervoor, probeert Ari wanhopig om een verrassingsfeestje voor haar in goede banen te leiden. De jongens proberen een interventie op touw te zetten voor Vince.