The team works alongside the FBI's Innocent Images Unit when a missing boy shows up on a website for sale to the highest bidder.
When Brennan is shot while working late at the Jeffersonian lab, she is rushed to the hospital in critical condition and struggles with visions of her mother that defy her usual logic.
Conrad comes under fire when a former patient files a malpractice lawsuit against him, putting Bell in a difficult position with Red Rock; the doctors perform a risky brain surgery; Mina discovers that Adaku has a dangerous heart condition.
The relationship between Robin and Regina grows increasingly more complex, as flashbacks show more information about the Snow Queen's life in Arendelle. Plus, Emma captures and interrogates the Snow Queen.