The doctors of Grey Sloan Memorial must contend with the COVID-19 pandemic; an unintentionally started fire has first responders from Station 19 bringing patients into the hospital for treatment.
Bailey finds herself in the middle of an argument with patients' families as they await news about their children who were injured in a fire; Winston surprises Maggie; Amelia and Link try to have some fun as new parents.
An elusive girl may hold the key to a mystery that brings the team to Asia. Meanwhile, a secret jeopardises Skye's relationship with the team.