On his first day as an intern, an idealistic Dr Devon Pravesh faces the harsh realities of medical care. Resident Conrad Hawkins teaches him unconventional methods for treating patients.
Conrad contemplates his future; Devon is presented with an amazing career opportunity out of state; Ian is faced with a devastating diagnosis; Kit and Bell celebrate their engagement; Padma receives some highly anticipated news.
When a police officer brings in an injured criminal, the staff must keep him alive. Nic gets roped into a surgical rotation with Cain that leaves her questioning the way he operates.
The doctors face new rules and doctors, as Red Rock Mountain Medical takes over the hospital.
When one of the doctors is found unconscious in an elevator at Chastain, the staff frantically retraces his steps to figure out the cause; Bell helps Kit make a decision about a new neurosurgeon joining the team at Chastain.