People become afflicted by mysterious diseases when their hearts and minds are affected by the mysterious; Koto, a girl who produces mayonnaise from her eyes, visits Dr. Ramune.
Ramune is visited by Kengo, a young man whose penis has turned into a chikuwa fish cake; though there must be some reason for it, Kengo refuses to talk.
Ramune uses his Shoji Vision to invite Kuro to a mysterious item shop; Kuro discovers the mysterious item shop Akatsuki at his destination; at first glance, the store appears to be a candy shop, but mysterious items are sold in the back.
Takaharu, a high school student whose fingertips have turned into chili peppers, comes to see Ramune; he seems to have some idea as to why he's haunted by the mysterious.
A boy named Rio comes to the shrine; his mother is afflicted by a mysterious disease that has turned her ears into pot stickers; his mother claims not to know what the cause is, but she is distraught.
So long as people have hearts, there will be those with worries and concerns; those hearts are then invaded by something strange, causing them to show physical symptoms; these ailments, called mysterious diseases, exist unseen to most people.
Yuma Uchida
Ramune
Takuma Nagatsuka
Kuro
Kana Ueda
Ayame
Nobuhiko Okamoto
Niko
Junichi Suwabe
Momiji