Monica Garcia

Lisbon goes undercover as a prison inmate in order to get a convict to turn on her boyfriend who is the leader of the high-end car theft ring.

Cristina Yang has little sympathy for Constance Ferguson (special guest star Rosanna Arquette), a prison inmate who jeopardizes her health just to get out of solitary confinement. Meanwhile the interns all keep careful watch on the family of premature quintuplets with a variety of serious health challenges, Izzie's anger at Alex reaches boiling point, and Dr. Addison Shepherd decides to teach Izzie a very painful lesson.

Sheldon get upset about his career, the destruction of the comic book store and Leonard and Penny's future living arrangements. Howard and Bernadette can't keep hold of a carer for his mother.

Lynette feels her mother is marrying Frank for all the wrong reasons, and tries to talk her out of it. Meanwhile, Susan tries to befriend a curmudgeonly man during her dialysis sessions who has given up on ever finding a kidney donor.

Sheldon's fear of germs leads him to detention when flu season hits Medford and he goes to extremes to stay healthy.

JD is sick of perfect intern Keith and he's not the only one. After Elliot's relationship with Keith is revealed, the other interns think he is getting special attention.