Distraught Niki reveals her recent personal struggles to a friend; Matt assists Audrey's investigation into a bizarre murder; Hiro questions his heroism; Nathan and his wife strategize to win the congressional election.
The identity of the shooter is revealed, throwing Peter and Matt into uncharted territory; Sylar declares war on the Company and attacks its primary facility, but finds more than he expected on Level 5.
Nathan and Tracy try to free themselves, Maya, and Suresh's other test subjects; Elle returns with a surprise for Claire and her family; Angela tries to convince Sylar to save Peter.
Peter, Nathan, Matt and Hiro clash because of Adam's pursuit of the deadly virus; Micah turns to his mother to help save Monica; Maya learns how much of a monster Sylar is; Elle tries to get back into her father's good graces.
When four powerful villains take hostages at a bank, Angela sends H.R.G. and his shocking new partner in after them; Claire asks Meredith to show her how to fight; Suresh finds himself unprepared when an experiment yields unexpected results.