A young man, Peter Romancek, and his mother move to the town of Hemlock Grove. The town becomes restive after a young girl's corpse is found and strange rumors about Peter's nature lead the townsfolk to suspect him.

Roman confronts Peter, who was investigating the scene of the crime. They become friends, with Peter sharing his secret with Roman. Meanwhile, Letha discovers that she is pregnant.

A second body is found by Christina, a local student. Dr. Clementine Chasseur arrives in town to investigate the murders. Meanwhile, Roman decides to find the killer on his own and asks for Peter's help.

Letha starts feeling attracted to Peter, who looks for the help of his cousin Destiny to use her powers in order to track down the murderer. However, to do that, Roman and Peter must bring her some remains of one of the victims and they get in trouble when the police arrives at the cemetery with the same idea.

Peter brings the remains to Destiny and gets some clues about the murders. Meanwhile, a gala is held at the Godfrey Enterprises' Tower, where things become hectic. Dr. Chasseur remembers what she had to do to join the Order of the Dragon.

Peter and Roman's investigation takes them to the Godfrey's old steel mill, where they find a missing piece of the puzzle. Meanwhile, Christina has a date with a friend, whom she attacks when visions of the body she found begin to torment her.