The BAU heads south to investigate a fast-moving UnSub whose signature matches that of a serial killer from 30 years ago. Also, the team learns that someone is tracking their cases and replicating crimes the BAU is solving.

Tiana seeks help from traveling soothsayer Dr. Facilier. But when it's revealed that he has an ulterior motive, she's forced to take matters into her own hands. In Hyperion Heights, Sabine and Jacinda take on a risky business venture, but the strength of their friendship is tested when Victoria interferes with their plans. Meanwhile, Ivy recruits Henry to investigate Victoria, and Roni makes a discovery that could change her relationship with Henry forever.

Kenny joins Drew at his MMA veteran's support group and finds himself in the fight of his life. Jordan and Cain treat casualties from a hotel fire, while Shannon follows a hunch to help save a young victim. Paul's superstar sister, Dr. Bella Cummings, pays a visit to San Antonio Memorial and provides desperately needed support during a busy shift. Meanwhile, TC finally returns home, forcing him to deal with Topher's death.