Protein Folding, Misfolding, and Disorder

S1, E5: Discover how proteins fold into complex shapes, often with the help of molecular chaperones. Then learn the deadly consequences of proteins that do not fold properly, leading to degenerative conditions such as Alzheimer’s, Parkinson’s, and prion diseases. Also look at intrinsically disordered proteins, which lack a fixed structure, permitting flexible interactions with other biomolecules.