Based on Lois Duncan's children's book series, Hotel For Dogs follows orphaned siblings Andi (Emma Roberts) and Bruce (Jake T. Austin) who secretly care for their beloved dog Friday while they live with self-absorbed, dog-hating foster parents. After Friday runs into a condemned old building, Andi and Bruce discover two dogs already living in the once-grand hotel and decide the place would make a perfect safe haven for the city's strays. With Bruce's knack for expertly engineered contraptions and the help of three local teens, the young animal lovers christen their little sanctuary the Hotel for Dogs.